Facts that affect the Glymphatic System

Sleep: It works best during sleep. Poor sleep or sleep disorders impair its function.

Hydration: Dehydration can reduce CSF flow, slowing the system.

Aging the glymphatic system becomes less efficient with age, contributing to a buildup of waste in the brain.

Exercise: Physical activity enhances lymphatics function by improving circulation.

Diet: Omega-3 fatty acids and a diet rich antioxidants  support brain health.

Glympatics and neurological diseases

Impaired glymphatic function has been liked to:

Alzheimer’s disease: inefficient clearance of beta-amylios contributes to plaque build up

Parkinsons diseace: accumulatuon of alpha-synuclein protiens

Traumatic Brain Injury (TBI): Can disrupt glymphatics pathways, leading to chronic inflammation